TY - JOUR AU - Pereira-Leal, Jose B. AU - Levy, Emmanuel D. AU - Kamp, Christel AU - Teichmann, Sarah A. PY - 2007 DA - 2007/04/05 TI - Evolution of protein complexes by duplication of homomeric interactions JO - Genome Biology SP - R51 VL - 8 IS - 4 AB - Cellular functions are accomplished by the concerted actions of functional modules. The mechanisms driving the emergence and evolution of these modules are still unclear. Here we investigate the evolutionary origins of protein complexes, modules in physical protein-protein interaction networks. SN - 1474-760X UR - https://doi.org/10.1186/gb-2007-8-4-r51 DO - 10.1186/gb-2007-8-4-r51 ID - Pereira-Leal2007 ER -