Expression conservation. (a) Controls for the ICC algorithm. ICC was applied ten times with randomly chosen initial weights (red), and ten times with randomly selected subsets of the expression conditions (blue). The correlations between these controls and expression conservation (from the original application) are shown after one to ten iterations. (b) Expression conservation values were calculated by ICC for all S. cerevisiae-C. albicans orthologs (solid black), duplicates from the WGD and their C. albicans ancestors (solid grey; both duplicates from each pair were compared to their ancestor), and randomly selected S. cerevisiae-C. albicans gene pairs (dashed black). Distributions are shown for bins of 0.1.