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Figure 8 | Genome Biology

Figure 8

From: Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription

Figure 8

Effect of RNAP II inhibitor α-amanitin on the abundance of protein-coding, antisense TIN, sense TIN and antisense PIN RNAs. Lines on each panel represent various transcripts for which the expression levels differed significantly between α-amanitin-treated prostate cells and untreated control cells. Each sample replica is shown in one column. Transcripts were selected by a SAM two-class test (FDR <0.2% to 2%) combined with a signal-to-noise test (p ≤ 0.05). For each line, expression intensities were normalized between the two conditions and colored as a function of the number of standard deviations from the mean value; (a) 3,604 significantly affected protein-coding transcripts; (b) 265 significantly affected antisense TIN transcripts; (c) 326 significantly affected sense TIN transcripts; (d) 339 significantly affected antisense PIN transcripts.

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