Known interactors with the RBR protein. The interacting proteins for each region are boxed and are preceded by the name of the subfamily of RBR proteins with which they interact: A, Ariadne; A3, Parc; B, ARA54; D, dorfin; P, parkin; C, RNF144; X, XAP; U, Paul; T, TRIAD3. The additional amino-terminal domains present in some subfamilies of RBR proteins are highlighted in light blue and indicated by the domain abbreviation with the subfamily in which they are found in parentheses. UBL, ubiquitin-like domain; UBA, ubiquitin-associated domain; ZnF_RBZ, zinc finger; cullin, cullin-like domain; ARM/HEAT, Armadillo and HEAT repeats; APC10, anaphase-promoting complex subunit 10. A carboxy-terminal hydrophobic segment is present in the dorfins. Additional substrates and interactors are listed in Additional data file 1.