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Table 2 KEGG pathways of gene categories that are over-represented by targets of two or more miRNAs distinguished by schizophrenia

From: microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

KEGG Pathway Term

N

%

P value

HSA04810:REGULATION OF ACTIN CYTOSKELETON

43

2.81

1.7E-07

HSA04510:FOCAL ADHESION

45

2.94

3.5E-07

HSA04010:MAPK SIGNALING PATHWAY

41

2.68

3.9E-05

HSA04512:ECM-RECEPTOR INTERACTION

17

1.11

0.0029

HSA04070:PHOSPHATIDYLINOSITOL SIGNALING

18

1.17

0.0076

HSA04020:CALCIUM SIGNALING PATHWAY

28

1.83

0.0093

HSA00271:METHIONINE METABOLISM

6

0.39

0.0099

HSA04540:GAP JUNCTION

16

1.04

0.0109

HSA04530:TIGHT JUNCTION

18

1.17

0.0173

HSA04910:INSULIN SIGNALING PATHWAY

21

1.37

0.0193

HSA04630:JAK-STAT SIGNALING PATHWAY

22

1.44

0.0326

HSA04710:CIRCADIAN RHYTHM

5

0.33

0.0370

  1. N, number of potential target genes in pathway; %, percent of pathway genes that are targeted by differentiated miRNAs.
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Genome Biology

ISSN: 1474-760X

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