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Table 2 KEGG pathways of gene categories that are over-represented by targets of two or more miRNAs distinguished by schizophrenia

From: microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

KEGG Pathway Term N % P value
HSA04810:REGULATION OF ACTIN CYTOSKELETON 43 2.81 1.7E-07
HSA04510:FOCAL ADHESION 45 2.94 3.5E-07
HSA04010:MAPK SIGNALING PATHWAY 41 2.68 3.9E-05
HSA04512:ECM-RECEPTOR INTERACTION 17 1.11 0.0029
HSA04070:PHOSPHATIDYLINOSITOL SIGNALING 18 1.17 0.0076
HSA04020:CALCIUM SIGNALING PATHWAY 28 1.83 0.0093
HSA00271:METHIONINE METABOLISM 6 0.39 0.0099
HSA04540:GAP JUNCTION 16 1.04 0.0109
HSA04530:TIGHT JUNCTION 18 1.17 0.0173
HSA04910:INSULIN SIGNALING PATHWAY 21 1.37 0.0193
HSA04630:JAK-STAT SIGNALING PATHWAY 22 1.44 0.0326
HSA04710:CIRCADIAN RHYTHM 5 0.33 0.0370
  1. N, number of potential target genes in pathway; %, percent of pathway genes that are targeted by differentiated miRNAs.