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Table 1 CDK target sets used in this study

From: Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

Set

Ascertainment

Total

Definition of target

Positives

'Known'

Unknown, complex

12

Low-throughput experimental characterization

12

'Unbiased'

randomly chosen proteins

198

Score > 2 in high-throughput assay

18

'2+'

All S. cerevisiae proteins containing two or more matches to the 'strong' CDK consensus

385

Score > 2 in high-throughput assay

143

'1cc'

All S. cerevisiae proteins containing one match to the 'strong' CDK consensus and exhibiting cell cycle regulated transcription

137

Score > 2 in high-throughput assay

32

  1. Four cyclin-dependent kinase (CDK) target sets from Saccharomyces cerevisiae [11]. Note that only the high-throughput data contain 'negatives'. The 'strong' CDK consensus is S/T-P-X-R/K, where X represents any amino acid.