Table 2 ICDSs shown by resequencing to correspond to authentic mutations in both M. smegmatis mc2155 and ATCC607
From: Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?
ICDS number | 5' position | ORF number | Putative function | Functional classification |
|---|---|---|---|---|
0003 | 1169121 | 1094-1095 | Oxidoreductase | Intermediary metabolism |
0004 | 1232918 | 1164-1165 | Arsenic resistance protein | Cell wall, process |
0005 | 1277324 | 1200-1201 | Glycosyltransferase | Intermediary metabolism |
0006 | 1304141 | 1226-1227 | ABC transporter (permease) | Cell wall, process |
0007 | 1508649 | 1403-1404 | Sodium/proton antiporter | Cell wall, process |
0008 | 1510156 | 1405-1406 | Arginine/ornithine antiporter | Cell wall, process |
0009 | 1510156 | 1405-1407 | Arginine/ornithine antiporter | Cell wall, process |
0010 | 1510315 | 1406-1407 | Arginine/ornithine antiporter | Cell wall, process |
0011 | 1545509 | 1447 | Secreted immunogenic protein (Mpt70) | Cell wall, process |
0013 | 1645546 | 1552-1553 | Conserved hypothetical | Unknown |
0014 | 1650143 | 1557-1558 | Hypothetical | Unknown |
0015 | 1669043 | 1575-1576 | Hypothetical | Unknown |
0020 | 1922875 | 1848-1849 | Formate dehydrogenase, alpha subunit | Intermediary metabolism |
0021 | 1924487 | 1849 | Formate dehydrogenase, alpha subunit | Intermediary metabolism |
0023 | 2026072 | 1949-1950 | Hypothetical | Unknown |
0025 | 2097821 | 2019-2020 | Cytochrome P450 | Intermediary metabolism |
0029 | 2234814 | 2164-2165 | Substrate-CoA ligase | Lipid metabolism |
0033 | 2557504 | 2472-2473 | Sugar transporter | Cell wall, process |
0036 | 2877071 | 2816-2817 | Two-component system regulator | Cell wall, process |
0038 | 3161135 | 3097-3098 | O-methyltransferase | Intermediary metabolism |
0042 | 3351460 | 3281-3282 | Sugar ABC transporter | Cell wall, process |
0043 | 3410192 | 3341 | Fatty acid desaturase (DesA3) | Lipid metabolism |
0044 | 3442071 | 3378 | Dehydrogenase/reductase | Intermediary metabolism |
0045 | 3471038 | 3405-3406 | Hypothetical | Unknown |
0046 | 3506575 | 3443-3344 | Hypothetical | Unknown |
0049 | 3849109 | 3785 | Conserved hypothetical | Unknown |
0052 | 3930423 | 3862-3863 | Polyprenol-monophosphomannose synthase (Ppm1) | Cell wall, process |
0055 | 4172910 | 4102-4103 | Dehydrogenase | Intermediary metabolism |
0059 | 4551995 | 4464-4465 | Hypothetical | Unknown |
0063 | 5113475 | 5001 | Transporter | Cell wall, process |
0064 | 5127828 | 5017-5018 | Multidrug resistance efflux protein (Tap) | Cell wall, process |
0067 | 5238606 | 5122-5123 | Nitrate reductase (NarX) | Intermediary metabolism |
0070 | 5596138 | 5488 | Conserved hypothetical | Unknown |
0071 | 5639815 | 5527-5528 | Protein-glutamate methylesterase | Intermediary metabolism |
0074 | 6014123 | 5909-5910 | Hypothetical | Unknown |
0075 | 6071755 | 5963-5964 | Integral membrane protein | Unknown |
0078 | 6147983 | 6046 | AraC-family transcriptional regulator | Regulation |
0079 | 6260084 | 6152-6153 | Anion transporter | Cell wall, process |
0084 | 6846273 | 6761 | Oxidoreductase | Intermediary metabolism |
0085 | 6862121 | 6775 | Major facilitator transporter | Cell wall, process |
0086 | 6955671 | 6870-6871 | Glutamine transporter | Cell wall, process |
0087 | 6977889 | 6889-6890 | Thioredoxin | Intermediary metabolism |
0088 | 17247 | 0017-0018 | Hypothetical | Unknown |
0094 | 3456823 | * | Dihydrolipoamide dehydrogenase | Intermediary metabolism |