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Table 4 Number of loci containing nucleotides in register with the telomeric insertion*

From: Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

  Number of observed loci (%)  
No. of nucleotides in register with telomeric insertion Mouse Rat Human Chimpanzee No. of expected loci (%)
0 11 (23) 16 (25) 1 (20) 1 (33) (75)
1 or more 36 (77) 47 (75) 4 (80) 2 (67) (≤ 25)
2 or more§ 26 (55) 31 (49) 3 (60) 2 (67) (≤ 6.25)
3 or more 16 (34) 21 (33) 2 (40) 1 (33) (≤ 1.56)
4 or more¥ 8 (17) 11 (17) 1 (20) 0 (0) (≤ 0.39)
  1. * For this analysis we utilized the informative species-specific loci listed in Additional data files 4 and 6, namely 47 mouse, 63 rat, 5 human and 3 chimpanzee ITS loci. This class includes the loci in which the last nucleotide at the 3' end of the break is not in register with the inserted telomeric repeat insertion. This class includes all loci with in register nucleotides. This class, together with the previous class comprises the totality of the loci. §These loci are also included in the '1 or more' class. These loci are also included in the '1 or more and 2 or more' classes. ¥These loci are also included in the '1 or more, 2 or more and 3 or more' classes.