Phylogenetic analysis of the reticulon homology domains (RHDs) of selected RTNs and RTNLPs. Alignments were created using the ClustalW2 program  and the tree was generated with Phylo_win software . Bootstrap numbers are shown; the number of repetitions was 1,000. The tree was generated using the maximum likelihood method. GenBank accession numbers are as follows: H. sapiens RTN1A, NP_066959; H. sapiens RTN2A, NP_005610; H. sapiens RTN3A, NP_006045; H. sapiens RTN4A, NP_065393; M. musculus RTN1A, NP_703187; M. musculus RTN2B, NP_038676; M. musculus RTN3A, NP_001003934; M. musculus RTN4A, NP_918943; G. gallus RTN4, NP_989697; X. laevis RTN2A, NP_001089014; X. laevis RTN4, NP_001083238; D. rerio RTN4, NP_001018620; D. melanogaster Rtnl1A, NP_787987; C. elegans RET-1, NP_506656; S. cerevisiae RTNLA, NP_010077; A. thaliana RTNLB3, NP_176592.