Figure 13From: Conservation and divergence of gene families encoding components of innate immune response systems in zebrafishPhylogenetic tree of NACHT proteins shared by mammals and fish and diagram of their protein structures. In addition to the known proteins Nod1, Nod2, Nod3, Nod9, CIITA, and Apaf, this tree shows that a new protein is shared by all five species, which we have named NACHT-P1. The protein domain structure diagram shown next to NACHT-P3 is representative of the majority of the novel fish proteins. Apaf, apoptotic protease activating factor; CIITA, major histocompatibility complex class II, transactivator; Nod, nucleotide oligomerization domain containing protein.Back to article page