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Table 3 The most over-represented level 4 GO annotations in the Biological process and Molecular function categories for each of the eight clusters of diurnal genes, using all diurnal genes as background distribution

From: Genome-wide expression profiling and bioinformatics analysis of diurnally regulated genes in the mouse prefrontal cortex

Cluster

GO level 4 annotation

Count

P value

FDR (%)

Biological process

    

1

Protein transport

49

1.6e-4

0.2

 

Establishment of protein localization

49

2.7e-4

0.4

 

Intracellular transport

44

1.3e-3

1.8

 

Establishment of cellular localization

44

1.8e-3

2.4

 

Cellular localization

44

1.8e-3

2.4

 

Vesicle-mediated transport

25

1.2e-2

15

2

M phase

12

3.0e-3

4.1

3

Phosphorus metabolism

44

3.4e-4

0.5

 

Biopolymer metabolism

97

1.9e-3

2.5

4

None

   

5

Response to protein stimulus

8

5.3e-3

7.2

6

Vitamin metabolism

7

1.5e-2

18.6

7

Generation of precursor metabolites and energy

20

1.3e-2

16.6

8

Cellular biosynthesis

25

7.0e-3

9.3

 

Antigen processing

4

9.2e-3

12.0

 

Macromolecule biosynthesis

17

1.7e-2

21.4

Molecular function

    

1

Guanyl nucleotide binding

22

1.4e-2

17.0

2

None

   

3

None

   

4

None

   

5

Voltage-gated ion channel activity

11

5.7e-4

0.8

 

Alkali metal ion binding

8

5.4e-3

6.9

 

Calcium ion binding

19

1.0e-2

12.7

 

Ion channel activity

12

2.1e-2

24.9

6

None

   

7

None

   

8

None

   
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Genome Biology

ISSN: 1474-760X

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