Figure 3

Common and unique aspects in the transcription response of spores to glucose. (a) Venn diagram comparing the genes induced during the first hour of spore germination, exit from stationary phase [10] or upon addition of glucose to vegetative cells starved of glucose [19]. A gene was defined as 'induced' if its average expression level during the first hour of the experiment was induced by at least two-fold relative to that before the addition of glucose or glucose-rich media. The area in the Venn diagram is proportional to the number of genes [46]. The correlations between changes in gene expression of all approximately 6,000 genes are indicated for pairs of experiments. Change in gene expression is the average change in expression during the first hour of the experiment relative to gene expression before the addition of glucose or glucose-rich media. (b,c) The average expression ratio during the same experiments as in (a) of genes that are related to specific GO terms (b) or in specific modules [16] (c).