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Figure 5 | Genome Biology

Figure 5

From: GeneChip analysis of human embryonic stem cell differentiation into hemangioblasts: an in silicodissection of mixed phenotypes

Figure 5

Ingenuity pathway analysis identified a network of genes expressed in EB and BC data sets associated with VEGF. In the EB data set, VEGF is associated with 35 'focus' genes, including KDR, FLT1, NRP1, and NRP2. In the BC data set, 13 focus genes were associated with VEGF, even though it is not present in the data set. The intensity of the node color indicates the degree of expression. Nodes are displayed using various shapes that represent the functional class of the gene product (diamond-enzymes, ovals-transcription factors, triangles-kinase, circles-others). A solid line indicates a direct interaction while a dashed line indicates an indirect interaction. A line without an arrowhead indicates binding and a plus sign indicates that othernetworks contain this gene product.

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