On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees

Table 4 Analysis of genes according to their position in relation to rearrangements

	Genes in rearranged versus colinear chromosomes			Genes within versus outside inversions (excluding HSA2, PTR12, PTR13)			Genes outside inversions versus genes in colinear chromosomes (excluding HSA2, PTR12, PTR13)
	Colinear	Rearranged	P value	Outside	Inside	P value	Colinear	Outside	P value
N	2,677	3,127		2,072	610		2,677	2,072
K_I	0.0122	0.0120	0.001	0.0120	0.0117	< 0.001	0.0122	0.0120	0.027
K_A	0.0030	0.0028	0.036	0.0027	0.0028	0.648	0.0030	0.0027	0.014
K_S	0.0131	0.0125	0.122	0.0127	0.0119	0.119	0.0131	0.0127	0.518
K_A/K_I	0.2442	0.2290	0.080	0.2255	0.2346	0.504	0.2442	0.2255	0.038

Comparison of genes in regions involved in rearrangements versus genes in colinear chromosomes or regions. Genes in breakpoints are included.

ISSN: 1474-760X