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Table 2 Estimated exponential rates associated with replacement turnovers of different TFBSs

From: Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools

TFBS

Promoter

λmean

λmedian

E2F

Simulated

0.0832

0.0724

E2F

Real

0.0833

0.0756

MycMax

Simulated

0.2200

0.2293

NFκB

Simulated

0.1032

0.0918

  1. The probability of replacement turnover in evolution can be predicted by an exponential cumulative distribution function of divergence distance: RTR = 1 - Exp (-λ × d). λ mean and λ median are estimated rates for mean and median values, respectively.
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Genome Biology

ISSN: 1474-760X

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