Figure 1

Evolution of D. melanogaster CRP gene duplicates and CRP-like genes. The likely pattern of emergence of CRP duplicate genes with restricted expression (blue), CRP-like genes (green) and CRP pseudogenic fragments (brown) in the lineage leading to D. melanogaster is shown. RpL34b is shown in black text: this is the only case where the newly emerged duplicate gene (RpL34b), rather than precursor gene (RpL34a), acts as the principal gene copy. The relative placement of CG11386 and CG33222 is consistent with the model presented by Stewart and Denell [86]. The dendrogram is based on that given in reference [140], in which the relationships among the Drosophilidae are taken from [149]; note that the branch lengths do not accurately reflect evolutionary time.