Figure 3

Relative expression of DNA packaging gene set relative to the overall transcriptome. The ratio of expression level of each gene in samples of infants that went on to develop bronchopulmonary dysplasia (BPD) against those who did not is plotted against the expression value in the infants without BPD. Overall, the entire transcriptome (small closed circles) is distributed around the horizontal 1.0 line (equal in BPD and control infants). However, the 229 members of the DNA packaging gene set (large squares) are significantly biased below the 1.0 line (NT_k q value = 0). This figure illustrates that, individually, none of the DNA packaging gene set fell significantly outside the range of variation of the entire transcriptome.