Table 2 The relationship between dispensability and functional category for both WGDs and SSDs

Over-represented in set of essential genes

   0003824

Catalytic activity

32.5

46.5⁺

35.8

   0005488

Binding

17.8

10.7^-

17.9

   0016740

Transferase activity

11.1

9.4

15.0⁺

   0003676

Nucleic acid binding

8.5

2.2^-

10.1

   0005515

Protein binding

7.5

5.5

5.9

   0005198

Structural molecule activity

5.8

8.1

9.2⁺

   0030528

Transcription regulator activity

5.6

2.6^-

7.0

   0016772

Transferase activity, transferring phosphorus-containing groups

5.1

4.6

8.7⁺

   0016462

Pyrophosphatase activity

4.6

12.4⁺

3.1

   0016817

Hydrolase activity, acting on acid anhydrides

4.6

12.4⁺

3.1

   0016818

Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

4.6

12.4⁺

3.1

   0017111

Nucleoside-triphosphatase activity

4.2

12.0⁺

2.7

   0003723

RNA binding

4.0

0.7^-

3.1

   0016887

ATPase activity

3.2

8.5⁺

1.8

   0016874

Ligase activity

2.2

1.7

2.0

   0003702

RNA polymerase II transcription factor activity

2.1

0.7

2.7

   0004386

Helicase activity

1.4

4.4⁺

0.4

   0016779

Nucleotidyltransferase activity

1.4

0.0^-

1.0

   0016251

General RNA polymerase II transcription factor activity

1.1

0.4

0.1^-

Under-represented in set of essential genes

   0005215

Transporter activity

7.1

15.5⁺

6.2

   0016491

Oxidoreductase activity

4.5

9.0⁺

5.3

   0015075

Ion transporter activity

2.5

5.9⁺

1.6

   0008324

Cation transporter activity

2.1

5.2⁺

1.1