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Table 2 The relationship between dispensability and functional category for both WGDs and SSDs

From: All duplicates are not equal: the difference between small-scale and genome duplication

GO ID Description % all ORFs % SSDs % WGDs
Over-represented in set of essential genes
   0003824 Catalytic activity 32.5 46.5+ 35.8
   0005488 Binding 17.8 10.7- 17.9
   0016740 Transferase activity 11.1 9.4 15.0+
   0003676 Nucleic acid binding 8.5 2.2- 10.1
   0005515 Protein binding 7.5 5.5 5.9
   0005198 Structural molecule activity 5.8 8.1 9.2+
   0030528 Transcription regulator activity 5.6 2.6- 7.0
   0016772 Transferase activity, transferring phosphorus-containing groups 5.1 4.6 8.7+
   0016462 Pyrophosphatase activity 4.6 12.4+ 3.1
   0016817 Hydrolase activity, acting on acid anhydrides 4.6 12.4+ 3.1
   0016818 Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.6 12.4+ 3.1
   0017111 Nucleoside-triphosphatase activity 4.2 12.0+ 2.7
   0003723 RNA binding 4.0 0.7- 3.1
   0016887 ATPase activity 3.2 8.5+ 1.8
   0016874 Ligase activity 2.2 1.7 2.0
   0003702 RNA polymerase II transcription factor activity 2.1 0.7 2.7
   0004386 Helicase activity 1.4 4.4+ 0.4
   0016779 Nucleotidyltransferase activity 1.4 0.0- 1.0
   0016251 General RNA polymerase II transcription factor activity 1.1 0.4 0.1-
Under-represented in set of essential genes
   0005215 Transporter activity 7.1 15.5+ 6.2
   0016491 Oxidoreductase activity 4.5 9.0+ 5.3
   0015075 Ion transporter activity 2.5 5.9+ 1.6
   0008324 Cation transporter activity 2.1 5.2+ 1.1
  1. Gene Ontology (GO) categories significantly over-represented and under-represented (corrected P < 0.05) are sorted by abundance (1% cut-off). Significant over-representation and under-representation in the duplicate sets are denoted by superscript '+' and '-', respectively. ORF, open reading frame; SSD, small-scale duplicate; WGD, whole-genome duplicate.