Figure 9
Morphologic diversity of highly ambiguous Candida albicans cells in liquid culture. (a) C. albicans CAI-4 control cells. (b,c) Cells transformed with the pUA15 plasmid, carrying a S. cerevisiae tRNACAGLeu, exhibited diverse morphologic types that ranged from large circular or ovoid opaque-like cells (Op) that contained large vacuoles, to pseudo-hyphal (Phy) and hyphal forms (Hy; arrows). (d) Opaque cells (ovoid) isolated from sectors of white colonies maintained in minimal media. (e) A small percentage of the pUA15 clones produced very long hypha.