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Table 2 Genes detected in the liquid association analysis shown in Figure 1

From: Finding disease candidate genes by liquid association

Gene ID

Location

Description

MBP

18q23*

Myelin basic protein

PRKCA

17q24.2*

Protein kinase C, alpha

SLC1A3

5p13.2†

Solute carrier family 1 (glial high affinity glutamate transporter), member 3

A2M

12p13.31*

α2-Macroglobulin

GRM3

7q21.12

Glutamate receptor, metabotropic 3

GFAP

17q21.31

Glial fibrillary acidic protein

CDR1

Xq27.1

Cerebellar degeneration-related protein 1, 34kDa

ROM1

11q12.3

Retinal outer segment membrane protein 1

CACNA1A

19p13.2

Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

GRIA3

Xq25

Glutamate receptor, ionotrophic, AMPA3

SOX21

13q32.1

SRY (sex determining region Y)-box 21

IL7R

5p13.2†

Interleukin 7 receptor

IGHG3

14q32.33*

Immunoglobulin heavy constant gamma 3 (G3m marker)

IGLJ3

22q11.1

Immunoglobulin lambda joining 3

HLA-A

6p21.33†

Major histocompatibility complex, class I, A

HLA-B

6p21.33†

Major histocompatibility complex, class I, B

HLA-C

6p21.33†

Major histocompatibility complex, class I, C

HLA-G

6p22.1†

HLA-G histocompatibility antigen, class I, G

B2M

15q21.1

β2-Microglobulin

PTPRC

1q31.3*

Protein tyrosine phosphatase, receptor type, C

EVI2A

17q11.2*

Ecotropic viral integration site 2A

TAP2

6p21.32*

Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

TRIM10

6p21.33†

Tripartite motif-containing 10

SIAT1

3q27.3

Sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)

MAG

19q13.12*

Myelin associated glycoprotein [M29273]

IRF1

5q23.3*

Interferon regulatory factor 1

APOE

19q13.31*

Apolipoprotein E

PDGFA

7p22*

Platelet-derived growth factor-α polypeptide [H89357]

SIAT8A

12p12.1

Sialyltransferase 8A

SOX4

6p22.3†

SRY (sex determining region Y)-box 4

SOX9

17q24.3†

SRY (sex determining region Y)-box 9

HLA-DQB1

6p21.32†

Major histocompatibility complex, class II, DQ beta 1

EPHA2

1p36.13

EphA2 [T74614]

GMFB

14q22.2

Glia maturation factor, beta

PDGFRA

4q12*

Platelet-derived growth factor receptor-α polypeptide [M21574]

PLP1

Xq22.2*

Proteolipid protein 1

KLK6

19q13.41

Kallikrein 6 (neurosin, zyme)

PMP2

8q21.13

Peripheral myelin protein 2

CTNND2

5p15.2*

Catenin delta 2 (neural plakophilin-related arm-repeat protein)

NTRK2

9q21.33

Neurotrophic tyrosine kinase, receptor type 2

PKP4

2q24.1

Plakophilin 4

  1. *Genes previously reported associated with MS. †Genes located within the previously reported MS susceptibility loci.