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Table 2 Scoring of immune infiltrate by immuno histochemistry

From: Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection

Pooled treatment groups

Δ Score post - pre-treatment

Within group p value

 

-3

-2

-1

0

1

2

3

 

CD56

        

   Imiquimod

0

0

1

12

6

1

0

0.03

   Vehicle

0

0

2

11

0

0

0

0.17

CD8

        

   Imiquimod

0

0

1

10

7

1

1

0.01

   Vehicle

0

0

0

9

1

2

0

0.22

CD4

        

   Imiquimod

0

0

1

12

7

0

0

0.03

   Vehicle

0

0

2

5

4

1

0

0.22

BCL-2

        

   Imiquimod

0

0

1

11

6

2

0

0.02

   Vehicle

0

0

2

9

1

1

0

0.72

  1. P values associated with the paired t-test for within group shifts relative to baseline. Δ Score refers to differences in infiltrate between EOT and pre-treatment samples using the scoring scale described in Materials and methods (IHC section).
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Genome Biology

ISSN: 1474-760X

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