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Table 2 Scoring of immune infiltrate by immuno histochemistry

From: Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection

Pooled treatment groups Δ Score post - pre-treatment Within group p value
  -3 -2 -1 0 1 2 3  
CD56         
   Imiquimod 0 0 1 12 6 1 0 0.03
   Vehicle 0 0 2 11 0 0 0 0.17
CD8         
   Imiquimod 0 0 1 10 7 1 1 0.01
   Vehicle 0 0 0 9 1 2 0 0.22
CD4         
   Imiquimod 0 0 1 12 7 0 0 0.03
   Vehicle 0 0 2 5 4 1 0 0.22
BCL-2         
   Imiquimod 0 0 1 11 6 2 0 0.02
   Vehicle 0 0 2 9 1 1 0 0.72
  1. P values associated with the paired t-test for within group shifts relative to baseline. Δ Score refers to differences in infiltrate between EOT and pre-treatment samples using the scoring scale described in Materials and methods (IHC section).