|
Pooled treatment groups
|
Δ Score post - pre-treatment
|
Within group p value
|
|---|
| |
-3
|
-2
|
-1
|
0
|
1
|
2
|
3
| |
|---|
|
CD56
| | | | | | | | |
|
Imiquimod
|
0
|
0
|
1
|
12
|
6
|
1
|
0
|
0.03
|
|
Vehicle
|
0
|
0
|
2
|
11
|
0
|
0
|
0
|
0.17
|
|
CD8
| | | | | | | | |
|
Imiquimod
|
0
|
0
|
1
|
10
|
7
|
1
|
1
|
0.01
|
|
Vehicle
|
0
|
0
|
0
|
9
|
1
|
2
|
0
|
0.22
|
|
CD4
| | | | | | | | |
|
Imiquimod
|
0
|
0
|
1
|
12
|
7
|
0
|
0
|
0.03
|
|
Vehicle
|
0
|
0
|
2
|
5
|
4
|
1
|
0
|
0.22
|
|
BCL-2
| | | | | | | | |
|
Imiquimod
|
0
|
0
|
1
|
11
|
6
|
2
|
0
|
0.02
|
|
Vehicle
|
0
|
0
|
2
|
9
|
1
|
1
|
0
|
0.72
|
- P values associated with the paired t-test for within group shifts relative to baseline. Δ Score refers to differences in infiltrate between EOT and pre-treatment samples using the scoring scale described in Materials and methods (IHC section).
