Figure 3

Gene expression changes localized to cytogenetic band 2F. Cytogenetic band 2F was analyzed for the relative expression values of Affymetrix annotated genes. The log₂ ratio of each gene (diamonds), plotted by genomic position, is displayed for: (a) B10^k PreS compared to B10^k S+; (b) B10^k S- compared to B10^k S+; and (c) B10^k S- compared to NOD^k S-. Comparisons of gene expression changes under these conditions were made by plotting the log₂ ratios for all genes within cytogenetic band 2F against each other (diamonds) and calculating the r² value. The distance from the origin thus reflects the degree of expression change. (d) Ratio of gene expression in B10^k PreS compared to B10^k S+ (y-axis) versus the ratio of expression in B10^k S- compared to B10^k S+ (x-axis). (e) Ratio of gene expression in B10^k S- compared to NOD^k S- (y-axis) versus B10^k S- compared to B10^k S+ (x-axis). In each case the probeset measuring Bim expression is indicated with a red diamond. All probesets with a relative change greater than +1 or less than -1 are shaded grey and annotated.