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Table 2 Results of applying JIGSAW with all available evidence

From: JIGSAW, GeneZilla, and GlimmerHMM: puzzling out the features of human genes in the ENCODE regions

 

Gene Sn

Gene Sp

Exon Sn

Exon Sp

Nuc Sn

Nuc Sp

Missed Genes

Missed Exons

Inserted Exons

JIGSAW-mRNA

48%

60%

76%

93%

84%

97%

17%

11%

4%

JIGSAW-All-EST

52%

52%

77%

88%

91%

91%

6%

10%

8%

JIGSAW-KnownGene

71%

74%

76%

95%

87%

96%

7%

12%

3%

JIGSAW-All

74%

70%

80%

92%

93%

94%

3%

7%

6%

KnownGene

77%

73%*

78%

82%

89%

94%

13%

10%

4%

JIGSAW-EGASP

73%

66%

81%

89%

95%

92%

4%

6%

8%

  1. * KnownGene predicts multiple transcripts per gene locus with transcript specificity of 47%. The percentage of test genes and exons that do not overlap a prediction are listed in the Missed Genes and Missed Exons columns, respectively. The rightmost column shows the percentage of predicted exons inserted into true introns. See text for details. Nuc, nucleotide; Sn, sensitivity; Sp, specificity.