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Table 1 Correlation of tissue specificities measured by relative entropy in CAGE and UniGene EST clusters

From: Transcriptional and structural impact of TATA-initiation site spacing in mammalian core promoters

Gene set

EST versus CAGE: Spearman rank correlation coefficient

Spearman rank correlation P value

Number of genes

Whole brain specific

216

1.10 × 10-3

17

Testis specific

48

9.68 × 10-2

9

Heart specific

40

1.48 × 10-2

10

Liver specific

20,898

1.32 × 10-6

66

Lung specific

92

1.81 × 10-2

12

Cerebellum specific

186

<2.20 × 10-16

20

Citric acid cycle

318

2.90 × 10-1

14

Ubiquitin-mediated proteolysis pathway

886

5.94 × 10-3

23

Housekeeping genes

2,208,352

8.54 × 10-6

263

All sets combined

5,269,164

<2.20 × 10-16

434

  1. Pair-wise correlations between tissue specificity values using CAGE and EST clusters was calculated as in the cor.test method in the R language [62], using Spearman correlation (two-sided test). CAGE, cap analysis of gene expression; EST, expressed sequence tag.