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Figure 5 | Genome Biology

Figure 5

From: Identification of 491 proteins in the tear fluid proteome reveals a large number of proteases and protease inhibitors

Figure 5

GO classification of tear fluid based on cellular localization. (a) Of the 491 proteins identified in the tear fluid, 200 were classified as intracellular proteins, while only 68 were classified as extracellular. As already described in the literature, the presence of intracellular proteins may be a result of cell death in the epithelium in close contact with the eye. (b) From the intracellular group, the great majority of proteins belongs to the cytoplasmic region, with some organelles being well represented, such as the lysosome (BiNGO p value of 6.9216E-8, the third highest score after cytoplasmatic and extracellular proteins).

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