Figure 2

A phylogenetic tree of mollusk, echinoderm, and vertebrate PGRPs, indicating their known and deduced functions. Bootstrap analysis and p-distance indicated as in Figure 1. Abbreviations: Ai, Argopecten irradians; Ar, Asterias rubens; Bt, Bos taurus; Cd, Camelus dromedaries; Cf, Canis familiaris; Dr, Danio Es, Euprymna scolopes; Gg, Gallus gallus; Hs, Homo sapiens; Mm, Mus musculus; Pt, Pan troglodytes; Rn, Rattus norvegicus; Sp, Strongylocentrotus purpuratus; Ss, Sus scrofa; Ten, Tetraodon nigroviridis; Xl, Xenopus laevis; Xt, Xenopus tropicalis. Accession numbers and references are listed in Table 1. The asterisk indicates that Es PGRP-4 is not a predicted amidase.