Co-evolution of transcription factors and their targets depends on mode of regulation

Table 1 Average number of targets of transcription factors classified based on conservation range

Type of targets	Entero-absent TFs	Entero-present TFs	Widely present TFs*
All targets^†	6.7 ± 8.9	13.9 ± 23.5	66.6 ± 85.2
Repressed targets	1.4 ± 2.6	6.2 ± 11.5	16.6 ± 17.8
Activated targets	5.1 ± 9	6.7 ± 12.8	42.3 ± 62.2

*The large standard deviations are due to several global TFs that regulate hundreds of targets. ^†Total targets, including repressed targets, activated targets anddually regulated targets.

ISSN: 1474-760X