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Figure 6 | Genome Biology

Figure 6

From: The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains

Figure 6

Multiple alignment of E2 (UBC)-like proteins with a special emphasis on bacterial versions. PDB identifiers of primary sequences derived from crystal structures are shaded in gold. Coloring is indicative of 55% consensus. The secondary structure, shown on the second line of the alignment, is derived from a general consensus of the secondary structure features from the different crystal structures shown in the alignment. Other features of the alignment are the same as in Figure 2, including coloring scheme, consensus abbreviations and secondary structure representations. Additionally, conserved polar residues (p; CDEHKNQRST) are colored blue. The strongly conserved proline and asparagine residues are colored purple brown respectively. The strongly conserved cysteine and histidine residues described in the text are shaded red and are also marked with an asterisk above their positions in the alignment. The major families of bacterial E2s are shown to the right. Also shown are the row numbers in Table 1, where a particular family is described. See the legend to Figure 2 for species abbreviations.

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