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Figure 2 | Genome Biology

Figure 2

From: Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineage

Figure 2

Distribution of length, percentage identity and shuffling categories of SCEs. SCEs were categorized based on their change in location and orientation in Fugu rubripes with respect to their location and orientation in the mouse locus. The entire locus, comprising the entire flanking sequence up to the next upstream and downstream gene was taken into consideration. Definitions of specific classes: (a) collinear SCEs (elements that have not undergone any change in location or orientation within the entire gene locus); (b) reversed SCEs (elements that have changed their orientation in the fish locus with respect to the mouse locus, but have remained in the same portion of the locus); (c) moved SCEs (elements that have moved between the pre-gene, post-gene and intronic portions of the locus); (d) Moved-reversed (elements that have undergone both of the above changes). (e) Frequency distribution of SCE length in base pairs. (f) Frequency distribution of percentage identity of SCE hits in fugu. SCE, shuffled conserved region.

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