Figure 4
From: Comparative genomics of Drosophila and human core promoters
8-mer localization in Drosophila expressed as a probability term, and characteristics of the most statistically relevant 8-mers. (a) The probability term P = -log10(1 - p) for the 13,552 8-mers with a maximum bin containing ≥15 members. The 298 DNA sequences above the line at P = 16, a 1 in 1 × 1016 (single sampling) chance of being random, were analyzed in more detail. (b) Clustering factors for both the positive (CF+) and negative strand (CF-) were plotted for the 298 most significant peaking 8-mers. The distribution falls into two distinct groupings; those that display a symmetric distribution on both strands (red circles) and those that cluster on only one strand (black circles). (c) A histogram showing the number of promoters containing each of the 15 motifs, grouped into three classes, DMp1 to 5, DMv1 to 5, and NDM1 to 5. We also present the common name and the consensus sequence.