A steganalysis-based approach to comprehensive identification and characterization of functional regulatory elements

Table 2 Discovered E2F motifs with G-score greater than 0.2

Motif	Z_g-score	Z-score	G-score	Number of occurrences	Number of promoters	Known motifs
Word cluster 1:
TTGGCGCCTC(-)	3.768	11.6	0.633	4	4	E2F(TTTYYCGYY)
TTTGGCGCCT(-)	4.384	9.5	0.438	5	5	E2F(TTTYYCGYY)
TGGCGCC(*)	3.006	5.6	0.255	20	20	E2F(TTTYYCGYY)
Word cluster 2:
TTTCCCGCCA(-)	-0.598	12.9	0.508	6	5	E2FANTRNR(TTTCCCGC)
TTTCCCGCC(+)	-0.613	4.7	0.289	5	5	E2FANTRNR(TTTCCCGC)
TTCCCGC(+)	0.236	5.7	0.285	36	32	E2FANTRNR(TTTCCCGC)
TTTCCCGCT(+)	0.227	4.3	0.273	7	7	E2FANTRNR(TTTCCCGC)

Motifs in cluster 1 are in motif region I (Figure 4) with Z_g-score greater than 3.0. Motifs in cluster 2 are in motif region II with Z_g-score less than 3.0. The motifs are marked with (+) if on the up strand, (-) if on the down strand or (*) if on both strands. Number of occurrences is the number of occurrences of a motif and Number of promoters is the number of promoters containing the motif.

ISSN: 1474-760X