Table 1 Correlation between enzymatic flux magnitude and evolutionary constraint Ka/Ks
From: Influence of metabolic network structure and function on enzyme evolution
Uptake | Maximum uptake rates (mmol/gDW/h) | Spearman's rank correlation (P value) with zero fluxes | Spearman's rank correlation (P value) without zero fluxes |
|---|---|---|---|
Glucose/oxygen | 15.3/2.4 | -0.28 (P = 3.8 × 10-3) | -0.25 (P = 3.6 × 10-6) |
Glucose/oxygen | 15.3/0.2 | -0.31 (P = 1.7 × 10-3) | -0.22 (P = 5.7 × 10-5) |
Glucose/oxygen | 15.3/0.01 | -0.26 (P = 9.3 × 10-3) | -0.21 (P = 1.2 × 10-4) |
Fructose/oxygen | 15.3/6.0 | -0.27 (P = 6.4 × 10-3) | -0.20 (P = 2.5 × 10-4) |
Fructose/oxygen | 15.3/0.2 | -0.25 (P = 1.3 × 10-2) | -0.20 (P = 1.8 × 10-6) |
Acetate/oxygen | 10.0/2.4 | -0.08 (P = 0.45) | -0.21 (P = 9.2 × 10-5) |
Acetate/oxygen | 5.0/5.0 | -0.010 (P = 0.39) | -0.19 (P = 3.7 × 10-4) |