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Table 2 Performance of reference based programs

From: Reference based annotation with GeneMapper

Program

Nucleotide

Exon

Genea

 

Sensitivity

Specificity

Sensitivity

Specificity

Sensitivity

Specificity

GeneWise

99.86

99.91

92.8

93.4

61.3

60.8

Projector

99.78

99.70

94.2

90.5

59.9

59.5

GeneMapper

99.88

99.94

97.2

97.8

81.7

81.7

  1. The Table summarizes the performance of GeneWise, Projector and GeneMapper on the Projector data set consisting of 491 orthologous human and mouse genes. The human annotation was used to predict the gene structure in the mouse sequence. Performance is reported in terms of nucleotide, exon, and gene level sensitivities and specificities. aGeneMapper predicts exactly one gene per reference annotation, and the number of predicted genes is equal to the number of genes in true or gold standard annotation. Consequently, gene sensitivity is equal to gene specificity for GeneMapper.