Figure 5
From: Ranked prediction of p53 targets using hidden variable dynamic modeling
Hidden variable dynamic modeling screening of upregulated genes. Model predicted profile (red) and experimental expression profile (black) of typical genes representing two classes of model prediction (class 1 and class 2). (a) Class 1 genes with good model score (M < 100) and high sensitivity P value (sensitivity Z score > 2; for example LRMP). (b) Class 1 genes with atypical expression profiles (for example, p53TG1); this profile occurs because of a low predicted degradation rate. (c,d) Two class 2 genes with low model score (M > 100) but high sensitivity P value (sensitivity Z score > 2; for example, TNFSF10 and IER3).