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Table 3 A core complement of exported proteins is conserved across Plasmodium

From: Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites

Chromosome Accession number Exons Transmembrane domain Microarray data Orthologs Comments
     R T S M SP G Pv Pk Py Pb Pc Pg  
1 PFA0210c 1 0 7.42 8.70 10.16 10.65 7.88 4.28 X   X   X X  
  PFA0585w 1 0 2.99 3.07 3.06 2.99 3.06 3.05 X X X    X  
  PFA0610c 2 cl 0 2.65 2.71 2.70 2.65 2.70 2.69 X X X X X X Hyp11
2 PFB0105c 2 cl 0 9.26 4.41 10.29 12.28 12.77 2.31 X       PHISTc
  PFB0110w 2 cl 0 3.37 3.48 3.48 3.40 3.47 3.46 X       Hyp11
  PFB0900c 2 cl 0 6.22 3.21 3.23 8.00 3.21 3.20 X X      PHISTc
  PFB0905c 2 cl 0 3.26 3.27 3.26 6.34 3.27 3.26 X X      PHISTc
  PFB0910w 2 cl 2 2.73 2.80 2.79 3.72 2.80 2.78 X   X     
  PFB0915w 2 cl 1 5.17 3.43 3.97 6.30 3.42 3.40 X X      LZ
3 PFC0075c 2 cl 0 3.13 3.21 3.20 3.15 3.20 3.19 X X      1 SNP
  PFC0090w 2 cl 1 6.51 3.22 6.31 10.36 3.25 3.20 X X X X X   1 SNP
4 PFD0495c 2 cl 1 2.63 2.69 2.68 2.76 2.69 2.67 X X X X X X  
5 PFE0055c 2 cl+2 0 2.37 2.37 2.35 8.07 2.37 2.36 X X      DNAj typeI
  PFE1595c 2 cl 0 2.64 2.70 2.69 2.65 2.69 2.69 X       PHISTc
7 MAL7P1.172 2 cl 0 9.65 6.52 5.03 9.47 3.62 3.60 X       PHISTc
8 MAL8P1.4 2 cl 0 5.46 3.35 3.34 3.49 3.35 3.33 X       PHISTc
  PF08_0137 2 cl 0 6.80 7.06 4.16 6.55 4.14 4.13 X X X X    PHISTc
9 PFI1725w 2 cl 0 3.84 3.36 3.35 5.47 3.36 3.33 X      X  
  PFI1750c 2 cl 0 2.71 7.53 2.68 2.64 2.68 2.67 X X     X Hyp11
  PFI1755c 2 cl 0 12.20 9.89 9.11 11.33 3.24 3.22 X       
  PFI1760w 2 cl 0 9.44 7.41 4.00 9.63 3.83 7.03 X       
  PFI1780w 2 cl 0 8.72 6.92 3.15 3.13 3.15 3.14 X X      PHISTc
10 PF10_0021 2 cl 0 6.01 3.51 3.84 5.38 3.50 3.49 X       PHISTc
  PF10_0022 2 cl 0 3.00 3.02 3.00 3.18 3.02 3.00 X       PHISTc
  PF10_0023 2 cl 2 3.12 3.19 3.18 3.13 3.17 3.16 X X      Hyp16
  PF10_0025 2 cl 1 8.65 2.84 3.64 10.34 2.86 2.85 X X      Hyp16
  PF10_0161 2 cl 0 2.60 2.66 2.65 2.61 2.68 2.65 X       PHISTc
  PF10_0162 2 cl 0 3.41 3.50 3.50 3.78 3.49 3.48 X X      PHISTc
  PF10_0163 2 cl 0 5.26 3.96 3.95 7.43 4.01 3.90 X X      PHISTc
11 PF11_0503 2 cl 0 7.08 3.09 3.06 3.04 3.08 3.07 X X      PHISTc
  PF11_0504 2 cl 0 3.50 3.55 3.55 3.51 3.55 3.54 X X      Hyp11
12 PFL0045c 2 cl 0 3.14 3.21 3.20 3.18 3.20 3.18 X       PHISTc
  PFL0600w 1 0 3.07 3.16 3.22 3.08 3.22 3.14 X X X     
  PFL1660c 2 cl+2 0 2.49 2.55 2.53 2.51 2.55 2.53 X X X     
13 PF13_0076 2 cl 1 6.85 6.35 3.76 6.28 3.73 3.73 X       
14 PF14_0731 2 cl 0 8.53 8.62 3.42 3.34 3.53 3.41 X       PHISTc
  1. For each conserved exported protein, this table presents exon structure, number of predicted transmembrane domains, protein localisation (where available), microarray expression (abbreviations same as in Table 2), conservation across the genus, and associated family. The text 'cl' in the exon column indicates a classic PEXEL structure with signal sequence in the first exon and PEXEL at the beginning of the second. For the microarray data group of columns, expression values for each member of the core list are presented. Values over 5 (indicating expression) in microarray data are highlighted in bold. Ortholog presence in other Plasmodium species is indicated by an X in the appropriate column of the Ortholog column group (Pv, P. vivax; Pk, P. knowlesi; Py, P. yoelii; Pb, P. berghei; Pc, P. chabaudi; Pg,P. gallinaceum). PlasmoDB IDs of genes conserved outside of the P. vivax and P. falciparum lineages are presented in bold.