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Table 4 DDI-PPI mapping based on both single domain PPIs and the structural DDIs

From: Evolutionary conservation of domain-domain interactions

Organisma E. coli yeast worm fly human
Number of PPIs 6,934 24,699 5,315 24,703 28,800
Number of PPIs with known domains (N) 6,038 18,202 3,351 14,939 25,004
Number of PPIs to which DDIs could be mapped (n) (%; n/N*100) 1,234 (20%) 5,048 (28%) 860 (26%) 3,983 (27%) 7,991 (32%)
  1. a Organism labeling: yeast: S. cerevisiae, worm: C. elegans, fly: D. melanogaster. DDI, domain-domain interaction; PPI, protein-protein interaction.