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Table 3 Common and unique DDIs by pair-wise organism comparison

From: Evolutionary conservation of domain-domain interactions

  E. coli a Yeast Worm Fly Human Total
E. coli 469 b (62%) c 211 (28%) 79 (10%) 64 (8%) 178 (23%) 759
yeast 211 (36%) 106 (18%) 163 (28%) 164 (28%) 352 (61%) 579
worm 79 (31%) 163 (65%) 24 (10%) 118 (47%) 193 (77%) 251
fly 64 (24%) 164 (60%) 118 (43%) 8 (3%) 239 (88%) 272
human 178 (20%) 352 (39%) 193 (22%) 239 (27%) 365 (41%) 897
  1. aOrganism labeling: yeast, S. cerevisiae; worm: C. elegans; fly, D. melanogaster.
  2. bValues in bold represent the DDIs unique to this organism. cThe percentage is calculated out of the total number of the organism's DDIs (right most column). The percentages in each line do not add up to 100% because there are DDIs that are shared by more than two organisms and they are counted more than once. DDI, domain-domain interaction.