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Table 2 GO terms associated with TE-rich human genes

From: Gene function and expression level influence the insertion/fixation dynamics of distinct transposon families in mammalian introns

   Over-represented TE types
GO term Description Alu L1 L2 LTR DNA transp. MIR
  Molecular function       N MCS IG
GO:0008009 Chemokine activity - - - - - 9 -0.91* -0.66
GO:0005125 Cytokine activity - - - - - 24 -0.42 -0.13
GO:0001584 Rhodopsin-like receptor activity - - - - - 19 -0.44 0.31
GO:0042379 Chemokine receptor binding - - - - - 9 -0.91* -0.66
GO:0005102 Receptor binding - - - - - 38 -0.45 -0.03
GO:0001664 G-protein-coupled receptor binding - - - - - 9 -0.91* -0.66
  Biological process         
GO:0050874 Organismal physiological process - - - - - 89 -0.57* 0.01
GO:0009607 Response to biotic stimulus - - - - - 70 -0.69* 0.36
GO:0006955 Immune response - - - - - 60 -0.67* 0.23
GO:0009611 Response to wounding - - - - - 31 -0.73* 0.11
GO:0006954 Inflammatory response - - - - - 24 -0.79* 0.06
GO:0006952 Defense response - - - - - 66 -0.7* 0.3
GO:0045087 Innate immune response - - - - - 26 -0.78* 0.07
GO:0016064 Humoral defense mechanism - - - - - 14 -0.65 0.24
GO:0009617 Response to bacteria - - - - - 13 -0.83* 0.34
GO:0009613 Response to pest, pathogen or parasite - - - - - 47 -0.72* 0.21
GO:0043207 Response to external biotic stimulus - - - - - 51 -0.74* 0.16
GO:0006950 Response to stress - - - - - 53 -0.72* 0.16
GO:0042742 Defense response to bacteria - - - - - 9 -0.98* 0.36
GO:0009605 Response to external stimulus - - - - - 65 -0.76* 0.19
GO:0009620 Response to fungi - - - - - 6 -1* 0.91
GO:0009628 Response to abiotic stimulus - - - - - 28 -0.83* 0.55
GO:0042221 Response to chemical substance - - - - - 27 -0.83* 0.7
GO:0050896 Response to stimulus - - - - - 85 -0.71* 0.31
GO:0006968 Cellular defense response - - - - - 14 -0.64 -0.14
GO:0007267 Cell-cell signaling - - - - - 37 -0.26 -0.32
GO:0042330 Taxis - - - - - 17 -0.78* -0.1
GO:0006935 Chemotaxis - - - - - 17 -0.78* -0.1
GO:0030574 Collagen catabolism - - - - - 7 -0.69 -0.77
  1. Significant differences are marked with an asterisk. DNA transp., DNA transposon; N, number of contributing genes; MCS, fractional intronic MCS density deviation (see text); IG, fractional igTEna deviation (see text).
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Genome Biology

ISSN: 1474-760X

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