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Table 1 Summary of dChip Gene Ontology classification of target mRNA populations

From: Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors

Cellular function

Gene Ontology group

U2AF (%)

PTB (%)

Array (%)

Gene expression

DNA binding

20.7

-

13.7

 

Transcription

16.9

-

11.9

 

Transcription regulator

13.5

-

8.5

 

Transcription factor

9.9

-

6.3

 

RNA binding

5.2

-

3.6

Cell cycle

Cell cycle

6.7

-

4.6

 

Regulation of cell cycle

4.1

-

2.7

Ubiquitination

Ubiquitin conjugating enzyme activity

1.6

1.7

0.5

Signaling

Small GTPase mediated signal transduction

2.7

3.5

1.5

Intracellular transport and vesicles

Intracellular protein transport

-

5.6

2.5

 

Vesicle-mediated transport

-

3.9

2.1

 

Golgi apparatus

-

3.6

1.9

 

Golgi trans face

-

0.5

0.1

  1. In the U2AF and PTB columns, '-' indicates that enrichment was not significant relative to the proportion of array genes belonging to the Gene Ontology group (P > 0.001). PTB, polypyrimidine tract binding protein; U2AF, U2 small nuclear RNP auxiliary factor.