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Table 1 Summary of dChip Gene Ontology classification of target mRNA populations

From: Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors

Cellular function Gene Ontology group U2AF (%) PTB (%) Array (%)
Gene expression DNA binding 20.7 - 13.7
  Transcription 16.9 - 11.9
  Transcription regulator 13.5 - 8.5
  Transcription factor 9.9 - 6.3
  RNA binding 5.2 - 3.6
Cell cycle Cell cycle 6.7 - 4.6
  Regulation of cell cycle 4.1 - 2.7
Ubiquitination Ubiquitin conjugating enzyme activity 1.6 1.7 0.5
Signaling Small GTPase mediated signal transduction 2.7 3.5 1.5
Intracellular transport and vesicles Intracellular protein transport - 5.6 2.5
  Vesicle-mediated transport - 3.9 2.1
  Golgi apparatus - 3.6 1.9
  Golgi trans face - 0.5 0.1
  1. In the U2AF and PTB columns, '-' indicates that enrichment was not significant relative to the proportion of array genes belonging to the Gene Ontology group (P > 0.001). PTB, polypyrimidine tract binding protein; U2AF, U2 small nuclear RNP auxiliary factor.