Figure 4
From: ProCAT: a data analysis approach for protein microarrays
Scheme for the signal scaling method. The signal of one spot on the array is normalized according to the distribution in its local neighborhood. For each spot, a surrounding window is chosen and all spots in this window are defined as its neighborhood. The signal of a center spot will then be normalized by comparing the local median and MAD with the average values. Norm, normalized signals; Origin, original signals.