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Figure 2 | Genome Biology

Figure 2

From: BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments

Figure 2

ROC curves depicting the performance of BoCaTFBS versus that of traditional methods. The traditional methods considered included centroid, Berg and von Hippel, PSSM, and consensus. False positive rate, also known as 1-specificity, is defined as the ratio of false positives over the sum of false positives and true negatives. True positive rate, also known as sensitivity, is defined as the ratio of true positives over the sum of true positives and false negatives. The error bars are 95% confidence intervals. Our BoCaTFBS method notably outperforms the other four methods. PSSM, positional specific scoring matrix; ROC, receiver operating characteristic.

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