How complete are current yeast and human protein-interaction networks?

Table 2 Prediction of the size of the yeast interactome

Dataset pair	Common baits	Estimated interactions in common search space	Projected interactome size (95% CI)
Gavin-Krogan (core) [27,28]	1,128	3,642	38,600 (37,800-39,500)
Ho-Gavin [16,17]	241	718	50,000 (47,700-53,000)
Ho-Krogan (core) [17,28]	282	1,109	69,000 (63,300-75,500)
Mean			52,500 (37,800-75,500)*

*The range of interactome sizes is the minimum and maximum from the confidence intervals (CI) generated from pairwise estimates.

ISSN: 1474-760X