Figure 2
From: How complete are current yeast and human protein-interaction networks?
The method of intersection analysis for estimating interactome size. In an interactome, or subspace of an interactome, of N true interactions, two independent assays of n1 and n2 interactions are expected, under the hypergeometric distribution, to share k interactions by random chance. As described in the text, we can use the observed intersection of interaction assays to estimate N.