Figure 5

Expression of component genes for three gene sets over the tissues in the expression atlas showing varying patterns of expression coherence among the component genes. Shown to the left of each gene set are the pathway measurements calculated using each of the five activation metrics. Expression data are log10 ratio relative to average (see Materials and methods). Magenta and cyan indicate higher and lower expression of a gene or pathway in a given sample, respectively. The x-axis of each plot lists the component genes for each of three pathways: (a) 'Microtubule-based process'; (b) 'Complement Activation, Classical Pathway'; and (c) 'tRNA aminoacylation'. All are GO Biological Process categories. The 52 tissues and cell lines used in this study are listed on the y-axes of each plot. Color axes are from -0.75 to 0.75 for gene expression log10 ratios (right plots). Missing data points are in white. For the activation metrics the color axes are normalized by the maximum and minimum values to range from 0 to 1.