Figure 2
Expression breadth versus the number of duplicate pairs. Red dots indicate singleton proteins, and black dots indicate duplicate proteins. The tissues tested are the 13 cluster-representing tissues. (a) The size of the dots represents the number of proteins that have the same number of duplicate pairs and the same expression breadth. The blue dots represent the average expression breadth of proteins with the same number of duplicate pairs. Sample size = 2731 proteins; Kendall's tau = -0.20; P value ≤ 2.2 × 10-16; 95% confidence interval = -0.22 to -0.17. (b) Proteins are ordered according to their number of duplicate pairs and collected into bins of at least 100 proteins. Each point represents a bin. Error bars indicate the standard deviation from the mean, obtained by bootstrapping.