Figure 1

A BLAST atlas diagram of eight enteric bacterial genomes, compared to the reference E. coli K-12 isolate MG1655. The outer five circles are other similar genomes from E. coli, S. enterica and Y. pestis (outer circle), while the inner three circles reflect the reduced genomes (from the innermost circle outwards) of B. aphidicola, B. cicadellinicola and S. glossinidius. Each colored circle represents the BLAST score of the best hit of the given bacterial proteome versus the gene at a given location in the reference E. coli MG1655 genome. Note that the scale is -log E-value, which means that the strongly colored regions have an E-value of less than 10^-100, which corresponds to a very good match. The locations of all the deletions engineered by Posfai et al. [5] are indicated outside the circles. Coding sequences of the reference genome (E. coli k-12 strain MG1655) are indicated as blue and red blocks, corresponding to genes orientated clockwise or counterclockwise. The gaps in the E. coli W3110 genome are due to rRNA operons and other non-coding RNAs, which do not show up on the protein BLAST results.