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Figure 3 | Genome Biology

Figure 3

From: Loss of LIN-35, the Caenorhabditis elegansortholog of the tumor suppressor p105Rb, results in enhanced RNA interference

Figure 3

A comparison of the genetic pathways that regulate RNAi and vulval development. A subset of the synthetic Multivulva B genes, designated the synMuv B(R) genes, negatively regulate vulval induction (redundantly with the synMuv A pathway), and also negatively regulate somatic and germline RNAi. In both processes the genes mes-4 and zfp-1 act genetically downstream of, or in parallel to, the synMuv B(R) genes. The identities of the synMuv B(R) genes are given below the figure.

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Genome Biology

ISSN: 1474-760X

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