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Figure 7 | Genome Biology

Figure 7

From: Challenging the spliceosome machine

Figure 7

Forced mismatch reveals A enrichment. Individual information was measured at nucleotide positions D-1 to D6 of donor sites flanking introns with lengths 1,024 to 4,095, using a reference set consisting of introns with lengths 8,192 to 16,383. The subset of these donor sites with individual information between 0 and 6 ((c) and (d): dataset I) was compared with the subset with individual information > 11 ((a) and (b): dataset II). Group information ((a) and (c)) and nucleotide counts ((b) and (d)) at each nucleotide position D-12 to D12 are plotted for the two subsets. The average standard deviation in information at nucleotide positions -12 to 12 is 0.030 for dataset I and 0.006 for dataset II. The maximum standard deviation for nucleotide counts at each nucleotide position is 0.026 for dataset I and 0.019 for dataset II. See [4] for a discussion of standard deviation calculations.

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