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Figure 1 | Genome Biology

Figure 1

From: Challenging the spliceosome machine

Figure 1

Information varies with intron and exon length. Donor and acceptor sites flanking either long or very short introns or exons have increased information. (a,b) The graphs show information profiles for nucleotide positions near donor and acceptor sites for nine sets of introns corresponding to progressively larger length ranges. We calculated the standard deviation at each of nucleotide positions D-2 to D10 and A-10 to A2. The maximum standard deviation observed was 0.073 bits (see [4] for explanation of standard deviation calculations). (c,d) Equivalent graphs based on varying exon length. The maximum standard deviation at each nucleotide position is 0.040 bits, except for the 2,048 to 4,095 size class where the value is 0.104 bits. Arrows mark nucleotide positions with characteristic information profile trends. Orange circles show which splice site is graphed relative to the varied intron or exon (double arrow).

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