Skip to main content

Table 3 Genes binding Hsf in both Drosophila and S. cerevisiae

From: Genomic analysis of heat-shock factor targets in Drosophila

FlyBase Fly ratio Yeast Yeast express NO-HS HS Lee ratio Lee p BLAST Yeast GO function
Acon 0.968 ACO1 2.876 0.833 0.516 1.86 6.90E-02 4.00E-274 Aconitate hydratase
Hsc70-5 1.686 SSC1 1.98 0.999 0.999 7.05 1.50E-04 6.60E-201 Protein transporter*
Hsp60 1.039 HSP60 2.608 0.997 0.997 2.33 1.50E-02 1.00E-177 Single-stranded DNA binding*
Cctgamma 1.275 CCT3 -0.28 0.646 0.343 1.85 7.80E-02 4.00E-162 Unfolded protein binding*
l(1)G0022 1.591 CCT6 0.063 0.714 0.921 1.73 8.60E-02 1.00E-136 Unfolded protein binding*
Hsc70Cb 2.164 SSE1 1.771 0.998 0.999 4.48 1.50E-03 1.70E-115 Unfolded protein binding*
CG8863 0.818 YDJ1 1.529 0.999 0.997 6.62 2.40E-04 2.00E-74 Chaperone regulator*
Cyp1 1.805 CPR1 1.251 0.996 0.995 10.83 3.40E-05 3.00E-65 Peptidyl-prolyl cis-trans isomerase
CG8258 1.962 CCT4 NA 0.385 0.055 1.85 7.80E-02 3.00E-55 Unfolded protein binding*
CG2918 1.100 SSA3 4.479 0.934 0.995 1.19 4.80E-01 7.00E-50 ATPase
DnaJ-1 2.375 SIS1 3.237 0.999 0.999 11.31 3.50E-05 7.00E-46 Unfolded protein binding*
Rab35 1.416 YPT32 0.338 0.269 0.343 1.98 4.30E-02 4.00E-40 GTPase activity
sktl 1.462 MSS4 1.042 0.712 0.879 1.91 4.80E-02 7.00E-35 Phosphatidylinositol kinase
CG4800 1.424 RBF18 0.03 0.872 0.964 2.13 1.50E-01 1.00E-33 Unknown
Cyt-c-d 0.932 CYC1 1.738 0.959 0.942 2.53 1.10E-02 4.70E-33 Electron carrier
mbf1 0.706 MBF1 NA 0.999 0.998 9.4 1.80E-04 2.00E-29 Transcription coactivator
CG1416 2.793 AHA1 3.288 0.999 0.999 9.14 5.60E-04 3.00E-28 Chaperone activator*
CG4500 1.37 FAA1 3.889 0.796 0.943 2.61 8.00E-03 9.00E-23 Fatty-acid-CoA ligase
CG32920 1.081 AHP1 1.547 0.983 0.984 3.81 1.10E-03 1.10E-19 Thioredoxin peroxidase
SH3PX1 0.877 SNX4 1.26 0.824 0.372 2.52 1.30E-02 6.30E-13 lipid binding
CG10973 1.532 FES1 3.541 0.997 0.993 NA NA 1.10E-10 Adenyl-nucleotide exchange factor
l(2)35Bg 0.755 DRE2 0.304 0.843 0.832 3.36 3.70E-03 5.00E-10 Unknown
CG12200 0.786 CST9 1.022 0.346 0.467 1.69 9.40E-02 8.70E-10 DNA binding
  1. The FlyBase gene ID is given, along with the average asinh ratio of Hsf enrichment. Yeast homologs are indicated by their Saccharomyces genome database (SGD) common names. The average heat-induced expression and ranking of Hsf binding in non-heat shocked (NO-HS) and heat shocked (HS) cells are from [28], the Lee ratio and Lee p are from [27]. BLAST scores are derived from searches at the SGD using the Drosophila sequences as probes. Gene Ontology (GO) functional classifications are for the yeast proteins; asterisks indicate stress-response proteins.